RESEARCH NEWS 2014-11-28 Research News The goal of BACE1 inhibition is to stop the production of toxic Aβ. However, a new study reports that at very high doses, the inhibitors may harm the very neurons they are meant to protect. Initial findings were presented by senior author ...
Fordham UniversityNew York, United States
PAPER Filser S, Ovsepian SV, Masana M, Blazquez-Llorca L, Elvang AB, Volbracht C, Muller MB, Jung CKE, Herms J
Biological Psychiatry. October 29, 2014.
Christchurch, United Kingdom
RESEARCH NEWS 2014-11-27 Research News The genomes of people with amyotrophic lateral sclerosis, even so-called sporadic cases, are often blemished by rare variants that may increase risk for the disease. Some unlucky folk tote two or even three of these potential risk alleles, ...
PAPER Grienberger C, Chen X, Konnerth A
Neuron. 2014 Mar 19;81(6):1274-81. Epub 2014 Feb 20 PubMed: 24560703
PAPER Mizuseki K, Buzsáki G
Cell Rep. 2013 Sep 12;4(5):1010-21. Epub 2013 Aug 29 PubMed: 23994479