PAPER Dichter MN, Schwab CG, Meyer G, Bartholomeyczik S, Dortmann O, Halek M
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PAPER Fonareva I, Oken BS
Physiological and functional consequences of caregiving for relatives with dementia.
Int Psychogeriatr. 2014 May;26(5):725-47. Epub 2014 Feb 10 PubMed: 24507463PAPER McCusker EA, Myers RH
Feasibility of Huntington disease trials in the disease prodrome.
Neurology. 2014 Mar 11;82(10):824-5. Epub 2014 Feb 7 PubMed: 24510495PAPER Jung Cheng C, Daggett V
Different misfolding mechanisms converge on common conformational changes: Human prion protein pathogenic mutants Y218N and E196K.
Prion. 2014 Feb 7;8(1) PubMed: 24509603PAPER Taschuk R, Marciniuk K, Määttänen P, Madampage C, Hedlin P, Potter A, Lee J, Cashman NR, Griebel P, Napper S
Safety, specificity and immunogenicity of a PrP(Sc)-specific prion vaccine based on the YYR disease specific epitope.
Prion. 2014 Feb 7;8(1) PubMed: 24509522PAPER Xie CL, Pan JL, Zhang SF, Gan J, Liu ZG
Effect of nicotine on L-dopa-induced dyskinesia in animal models of Parkinson's disease: a systematic review and meta-analysis.
Neurol Sci. 2014 Feb 9; PubMed: 24510151PAPER Carmo MR, Menezes AP, Nunes AC, Pliássova A, Rolo AP, Palmeira CM, Cunha RA, Canas PM, Andrade GM
The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis.
Neuropharmacology. 2014 Jun;81:142-52. Epub 2014 Feb 6 PubMed: 24508709PAPER Lai SW, Liao KF, Lin CL, Lin CC, Sung FC
Hearing loss may be a non-motor feature of Parkinson's disease in older people in Taiwan.
Eur J Neurol. 2014 Feb 10; PubMed: 24506292Maurizio Romano on Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.
COMMENT The pathogenetic mechanisms whereby TDP-43 alterations lead to ALS and FTLD are far from being clear. Defining these processes is challenging since TDP-43 is a "multitasking" protein, implicated in different aspects of RNA metabolism. Thus, befo
PAPER Vitaliano PP
An ironic tragedy: are spouses of persons with dementia at higher risk for dementia than spouses of persons without dementia?
J Am Geriatr Soc. 2010 May;58(5):976-8. PubMed: 20722822PAPER Egert S, Piechura H, Hambruch N, Feigel M, Blöchl A
Characterization of a peptide that specifically blocks the Ras binding domain of p75
Int J Pep Res Ther. 2007 Sep;13(3):413-21.Leucine-rich repeat kinase 2 (LRRK2)
ALZPEDIA Missense mutations in LRRK2 were first identified as a cause of Parkinson’s disease (PD) in 2004. Subsequent studies showed that these mutations account for up to 10 percent of familial cases, with even higher prevalence in Ashkenazi Jewish and North Afri
PAPER Sloan M, Alegre-Abarrategui J, Wade-Martins R
Insights into LRRK2 function and dysfunction from transgenic and knockout rodent models.
Biochem Soc Trans. 2012 Oct;40(5):1080-5. PubMed: 22988869PAPER Dzamko N, Halliday GM
An emerging role for LRRK2 in the immune system.
Biochem Soc Trans. 2012 Oct;40(5):1134-9. PubMed: 22988878PAPER Tsika E, Moore DJ
Contribution of GTPase activity to LRRK2-associated Parkinson disease.
Small GTPases. 2013 Jul-Sep;4(3):164-70. Epub 2013 Jun 10 PubMed: 24025585Current Filters
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