PAPER Sun J, Song F, Wang J, Han G, Bai Z, Xie B, Feng X, Jia J, Duan Y, Lei H
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PAPER Hernández-Rodríguez M, Correa-Basurto J, Martínez-Ramos F, Padilla-Martínez II, Benítez-Cardoza CG, Mera-Jiménez E, Rosales-Hernández MC
Design of multi-target compounds as AChE, BACE1, and amyloid-β(1-42) oligomerization inhibitors: in silico and in vitro studies.
J Alzheimers Dis. 2014;41(4):1073-85. PubMed: 24762947PAPER Xie J, Gabelle A, Dorey A, Garnier-Crussard A, Perret-Liaudet A, Delphin-Combe F, Bathsavanis A, Dauphinot V, Lehmann S, Mercier B, Desestret V, Roullet-Solignac I, Vighetto A, Krolak-Salmon P
Initial memory deficit profiles in patients with a cerebrospinal fluid Alzheimer's disease signature.
J Alzheimers Dis. 2014;41(4):1109-16. PubMed: 24762946PAPER Miyashita A, Wen Y, Kitamura N, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Furukawa K, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Nishizawa M, Suga M, Kawase Y, Akatsu H, Imagawa M, Hamaguchi T, Yamada M, Morihara T, Takeda M, Takao T, Nakata K, Sasaki K, Watanabe K, Nakashima K, Urakami K, Ooya T, Takahashi M, Yuzuriha T, Serikawa K, Yoshimoto S, Nakagawa R, Saito Y, Hatsuta H, Murayama S, Kakita A, Takahashi H, Yamaguchi H, Akazawa K, Kanazawa I, Ihara Y, Ikeuchi T, Kuwano R
Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population.
J Alzheimers Dis. 2014;41(4):1031-8. PubMed: 24762945PAPER Blanc F, Philippi N, Cretin B, Kleitz C, Berly L, Jung B, Kremer S, Namer IJ, Sellal F, Jaulhac B, de Seze J
Lyme neuroborreliosis and dementia.
J Alzheimers Dis. 2014;41(4):1087-93. PubMed: 24762944PAPER Lorenz R, Samnick S, Dillmann U, Schiller M, Ong MF, Faßbender K, Buck A, Spiegel J
Nicotinic α4β2 acetylcholine receptors and cognitive function in Parkinson's disease.
Acta Neurol Scand. 2014 Sep;130(3):164-71. Epub 2014 Apr 25 PubMed: 24762290PAPER Ma J, Choi BR, Chung C, Min SS, Jeon WK, Han JS
Chronic brain inflammation causes a reduction in GluN2A and GluN2B subunits of NMDA receptors and an increase in the phosphorylation of mitogen-activated protein kinases in the hippocampus.
Mol Brain. 2014 Apr 24;7:33. PubMed: 24761931Julian Pei
University of PennsylvaniaLansdale, United States
Maria Jose Sanchez Artero
PsiquiatriaGuadalajara, Spain
Does PET Tracer Reveal Severity of Parkinson's?
RESEARCH NEWS 2014-04-26 Research News In order to gauge the effectiveness of disease-modifying therapies for Parkinson’s, researchers are looking for a biomarker that measures how far a person’s disease has advanced. In the April 21 JAMA Neurology, scientists led by Kun-Ju Lin a
PAPER Hsiao IT, Weng YH, Hsieh CJ, Lin WY, Wey SP, Kung MP, Yen TC, Lu CS, Lin KJ
Correlation of Parkinson Disease Severity and 18F-DTBZ Positron Emission Tomography.
JAMA Neurol. 2014 Jun 1;71(6):758-66. PubMed: 24756323PAPER Frey KA, Koeppe RA, Kilbourn MR, Vander Borght TM, Albin RL, Gilman S, Kuhl DE
Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging.
Ann Neurol. 1996 Dec;40(6):873-84. PubMed: 9007092PAPER de la Fuente-Fernández R, Sossi V, McCormick S, Schulzer M, Ruth TJ, Stoessl AJ
Visualizing vesicular dopamine dynamics in Parkinson's disease.
Synapse. 2009 Aug;63(8):713-6. PubMed: 19391152Muscle-Boosting Therapy Fails in Phase 2 Trial for ALS
RESEARCH NEWS 2014-04-26 Research News The experimental muscle-stimulating drug Tirasemtiv was unable to improve amyotrophic lateral sclerosis (ALS) symptoms in a Phase 2 clinical trial, according to top-line data. Announced April 25 by the drug’s developer, South San Francisco-b
PAPER Shefner JM, Watson ML, Meng L, Wolff AA, Neals/Cytokinetics STUDY Team
A study to evaluate safety and tolerability of repeated doses of tirasemtiv in patients with amyotrophic lateral sclerosis.
Amyotroph Lateral Scler Frontotemporal Degener. 2013 Dec;14(7-8):574-81. Epub 2013 Aug 19 PubMed: 23952636Current Filters
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