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169078 RESULTS

MAPT P364S

MUTATIONS MAPT Exon 12 Point, Missense Coding Reduced ability to promote microtubule assembly compared with wild-type tau and an increased rate of tau aggregation. Increased chromosomal instability and copy number variations in lymphocytes and fibroblasts of ...

MAPT G366R

MUTATIONS MAPT Exon 12 Point, Missense Coding Reduced ability to promote microtubule assembly compared with wild-type tau, but similar aggregation kinetics. Increased chromosomal instability and copy number variations in lymphocytes and fibroblasts of mutation ...

Seqian Wang


McGill Centre for Studies in Aging
Montreal, Canada

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