PAPER Van Dijk D
SEARCH RESULTS
329930 RESULTS
PAPER Fraser GL, Riker RR, Coursin DC
Long-term cognitive impairment after critical illness.
N Engl J Med. 2014 Jan 9;370(2):184. PubMed: 24401070PAPER Pandharipande PP, Girard TD, Ely EW
Long-term cognitive impairment after critical illness.
N Engl J Med. 2014 Jan 9;370(2):185-6. PubMed: 24401069Michael Siciliano
Arlington, United States
Douglas Galasko on Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial.
COMMENT The TEAM-AD study revives interest in two areas: treatment with antioxidants such as vitamin E, and carrying out clinical trials in patients with mild to moderate AD to evaluate effects on disease progression. The findings of a benefit in the vitamin E tr
Benjamin Wolozin on Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models.
COMMENT This is a great article. The approach makes classic use of genetics to identify TDP-43 interactors, and in the process identifies a number of previously known and unknown players. The most interesting parts of the article for me are the experiments modula
Kurt A. Jellinger on Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study.
COMMENT Mielke et al. found that among older people with MCI but not cognitively normal (CN) individuals, those with a previous history of traumatic brain injury (TBI) have more Aß deposits in the brain than those without TBI history, suggesting that the etiology
PAPER Roberts GW, Gentleman SM, Lynch A, Graham DI
beta A4 amyloid protein deposition in brain after head trauma.
Lancet. 1991 Dec 7;338(8780):1422-3. PubMed: 1683421PAPER Rudelli R, Strom JO, Welch PT, Ambler MW
Posttraumatic premature Alzheimer's disease. Neuropathologic findings and pathogenetic considerations.
Arch Neurol. 1982 Sep;39(9):570-5. PubMed: 7115146PAPER Mathis CA, Kuller LH, Klunk WE, Snitz BE, Price JC, Weissfeld LA, Rosario BL, Lopresti BJ, Saxton JA, Aizenstein HJ, McDade EM, Kamboh MI, DeKosky ST, Lopez OL
In vivo assessment of amyloid-β deposition in nondemented very elderly subjects.
Ann Neurol. 2013 Jun;73(6):751-61. Epub 2013 Apr 17 PubMed: 23596051Sam Gandy on Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study.
COMMENT I think that there a lot of uncontrolled and unknowable variables at work here. The post traumatic brain injury (TBI) amyloidosis probably peaks very early and then might be resolved completely. I assume that the propensities for depositing and the speed
Does a Blow to the Head Mean More Amyloid Down the Road?
RESEARCH NEWS 2014-01-10 Research News Scientists disagree about the long-term consequences of head injury and whether it leads to Alzheimer's disease later in life (see AlzRisk entry). It may vary from person to person, suggests a report in the January 7 Neurology. Scientis
PAPER Wang HK, Lin SH, Sung PS, Wu MH, Hung KW, Wang LC, Huang CY, Lu K, Chen HJ, Tsai KJ
Population based study on patients with traumatic brain injury suggests increased risk of dementia.
J Neurol Neurosurg Psychiatry. 2012 Nov;83(11):1080-5. Epub 2012 Jul 27 PubMed: 22842203Familial ALS More Common Than Thought—Do We Need a New Definition?
RESEARCH NEWS 2014-01-10 Research News Amyotrophic lateral sclerosis runs in families more often than scientists originally thought. Researchers have claimed that 5 percent of ALS cases are inherited, with the remainder being sporadic, but a paper in the January 7 Neurology raise
PAPER Andersen PM, Al-Chalabi A
Clinical genetics of amyotrophic lateral sclerosis: what do we really know?
Nat Rev Neurol. 2011 Oct 11;7(11):603-15. PubMed: 21989245Current Filters
No filters selected