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329967 RESULTS

Maria Hanford


Non-profit organization
Forest Hills, United States

Jenifer Lee


University of California, Irvine
Irvine, United States

Tg4-42

RESEARCH MODELS Summary The Tg4-42 model was engineered to produce the peptide Aβ 4-42, one of a variety of N-terminally truncated Aβ species identified in the AD brain. The Aβ 4-42 peptide, which begins with a phenylalanine at position 4, may be a particularly abundant

TBA42

RESEARCH MODELS Summary The TBA42 model was designed to produce and secrete an N-terminally truncated Aβ peptide. TBA42, which stands for truncated beta-amyloid 42, specifically encodes an Aβ 3–42 peptide with a glutamine substituted for the naturally occurring glutamate

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