PAPER Lee SL, Thomas P, Hecker J, Faunt J, Fenech M
SEARCH RESULTS
329939 RESULTS
PAPER Xu Z, Shen X, Pan W, Alzheimer's Disease Neuroimaging Initiative
Longitudinal analysis is more powerful than cross-sectional analysis in detecting genetic association with neuroimaging phenotypes.
PLoS One. 2014;9(8):e102312. Epub 2014 Aug 6 PubMed: 25098835PAPER Littlejohns TJ, Henley WE, Lang IA, Annweiler C, Beauchet O, Chaves PH, Fried L, Kestenbaum BR, Kuller LH, Langa KM, Lopez OL, Kos K, Soni M, Llewellyn DJ
Vitamin D and the risk of dementia and Alzheimer disease.
Neurology. 2014 Sep 2;83(10):920-8. Epub 2014 Aug 6 PubMed: 25098535PAPER Bosboom PR, Almeida OP
Cognitive Domains and Health-Related Quality of Life in Alzheimer's Disease.
J Gerontol B Psychol Sci Soc Sci. 2014 Aug 5; PubMed: 25098526PAPER
Calming Alzheimer's agitation: a promising drug.
Johns Hopkins Med Lett Health After 50. 2014 Jun;29(5):8. PubMed: 25097959PAPER Ciccotosto GD, James SA, Altissimo M, Paterson D, Vogt S, Lai B, de Jonge MD, Howard DL, Bush AI, Cappai R
Quantitation and localization of intracellular redox active metals by X-ray fluorescence microscopy in cortical neurons derived from APP and APLP2 knockout tissue.
Metallomics. 2014 Oct;6(10):1894-904. Epub 2014 Aug 7 PubMed: 25098278PAPER Mo C, Renoir T, Hannan AJ
Ethological endophenotypes are altered by elevated stress hormone levels in both Huntington's disease and wildtype mice.
Behav Brain Res. 2014 Nov 1;274:118-27. Epub 2014 Aug 4 PubMed: 25101541PAPER Segura B, Baggio HC, Marti MJ, Valldeoriola F, Compta Y, Garcia-Diaz AI, Vendrell P, Bargallo N, Tolosa E, Junque C
Cortical thinning associated with mild cognitive impairment in Parkinson's disease.
Mov Disord. 2014 Oct;29(12):1495-503. Epub 2014 Aug 7 PubMed: 25100674PAPER Blautzik J, Vetter C, Schneider A, Gutyrchik E, Reinisch V, Keeser D, Paolini M, Pöppel E, Bao Y, Reiser M, Roenneberg T, Meindl T
Dysregulated daily rhythmicity of neuronal resting-state networks in MCI patients.
Chronobiol Int. 2014 Nov;31(9):1041-50. Epub 2014 Aug 6 PubMed: 25099642William Burke
United States
Ashkan Javaherian on Yeast Chaperone Melts Protein Aggregates
COMMENT The new findings by Jackrel and Shorter are an important and exciting extension of their previous work published earlier this year. They had previously engineered a variant of Hsp104 to reverse aggregation of misfolded proteins associated with Parkinson
Aaron Gitler on Yeast Chaperone Melts Protein Aggregates
COMMENT This manuscript by Jackrel and Shorter is an extension of the tour de force Cell paper published by these authors earlier this year (Jackrel et al., 2014). In that manuscript, they engineered the protein disaggregase Hsp104,which normally has no activity
Yeast Chaperone Melts Protein Aggregates
RESEARCH NEWS 2014-08-08 Research News Rejiggered chaperones untangle aggregates and refold mutant proteins associated with amyotrophic lateral sclerosis, frontotemporal dementia, and Parkinson’s disease, according to a paper in the July 25 Disease Models & Mechanisms online.
PAPER Couthouis J, Hart MP, Erion R, King OD, Diaz Z, Nakaya T, Ibrahim F, Kim HJ, Mojsilovic-Petrovic J, Panossian S, Kim CE, Frackelton EC, Solski JA, Williams KL, Clay-Falcone D, Elman L, McCluskey L, Greene R, Hakonarson H, Kalb RG, Lee VM, Trojanowski JQ, Nicholson GA, Blair IP, Bonini NM, Van Deerlin VM, Mourelatos Z, Shorter J, Gitler AD
Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis.
Hum Mol Genet. 2012 Jul 1;21(13):2899-911. Epub 2012 Mar 27 PubMed: 22454397Searching for Evidence of Neurodegeneration in the Blood
RESEARCH NEWS 2014-08-08 Research News Given the invasiveness and expense of measuring brain biomarkers for neurodegenerative diseases, researchers are searching for alternatives. Despite little success thus far, they continue to comb the complex jumble of proteins and molecules
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