More Accurate Ways to Measure CSF Aβ Debut

RESEARCH NEWS 2014-05-29 Research News There is a lot of talk about cerebrospinal fluid biomarkers for Alzheimer’s disease, but no robust test has arrived at local doctors’ offices yet. Before such tests can move to medical care clinics around the world from the research centers

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E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles.

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Phillip Alexander

IU School of Medicine
Indianapolis

Roberto Salinas

Xia Li

Shanghai Mental Health Center, Jiaotong University School of Medicine
Shanghai, China

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Regulation of energy balance by leptin.

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Han-Xiang Deng

PAPER Yang ZY, Li JM, Xiao L, Mou L, Cai Y, Huang H, Luo XG, Yan XX

[(3) H]-L685,458 Binding Sites are Abundant in Multiple Peripheral Organs in Rats: Implications for Safety Assessment of Putative γ-Secretase Targeting Drugs.

Basic Clin Pharmacol Toxicol. 2014 Dec;115(6):518-26. Epub 2014 Jul 4 PubMed: 24861611

PAPER Lahut S, Vadasz D, Depboylu C, Ries V, Krenzer M, Stiasny-Kolster K, Basak AN, Oertel WH, Auburger G

The PD-associated alpha-synuclein promoter Rep1 allele 2 shows diminished frequency in restless legs syndrome.

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PAPER Mioshi E, Hsieh S, Caga J, Ramsey E, Chen K, Lillo P, Simon N, Vucic S, Hornberger M, Hodges JR, Kiernan MC

A novel tool to detect behavioural symptoms in ALS.

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Epidemiology of amyotrophic lateral sclerosis in Emilia Romagna Region (Italy): A population based study.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Jun;15(3-4):262-8. Epub 2014 Feb 7 PubMed: 24863640

PAPER Tremolizzo L, Susani E, Aliprandi A, Salmaggi A, Ferrarese C, Appollonio I

Muscle ultrasonography for detecting fasciculations in frontotemporal dementia.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 May 27;:1-5. PubMed: 24863345

PAPER Heimrath J, Gorges M, Kassubek J, Müller HP, Birbaumer N, Ludolph AC, Lulé D

Additional resources and the default mode network: Evidence of increased connectivity and decreased white matter integrity in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 May 27;:1-9. PubMed: 24862983

PAPER Keren N, Scott KM, Tsuda M, Barnwell J, Knibb JA, Ellis CM, Leigh PN, Shaw CE, Al-Chalabi A

Evidence of an environmental effect on survival in ALS.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 May 27;:1-6. PubMed: 24862874

PAPER Beeldman E, Jaeger B, Raaphorst J, Seelen M, Veldink J, van den Berg L, de Visser M, Schmand B

The verbal fluency index: Dutch normative data for cognitive testing in ALS.

Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep;15(5-6):388-91. Epub 2014 May 27 PubMed: 24862654