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Levodopa-induced facial dystonia in a case of progressive supranuclear palsy.
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Cognitive impairments in multiple system atrophy of the cerebellar type.
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Sanjay Pimplikar on Has ApoE’s Time Come as a Therapeutic Target?
COMMENT There has been a growing realization that we need to expand AD drug targets beyond amyloid. Therefore, at first glance the news of ApoE as a potential therapeutic target would be welcomed. As other commentators have pointed out, the Holtzman paper present
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APOE epsilon4 genotype is associated with an earlier onset of chronic temporal lobe epilepsy.
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A small pool of vesicles maintains synaptic activity in vivo.
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Fluorescent in situ hybridization of synaptic proteins imaged with super-resolution STED microscopy.
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'The Genius of Marian'—A Personalized Look at Life with Alzheimer's
COMMUNITY NEWS 2014-05-30 Community News Pamela White of Dedham, Massachusetts, suffers from early onset Alzheimer's disease. Her diagnosis came at age 61, a year after she began writing a biography of her mother, the accomplished artist Marian Williams Steele, who died of Al
Gordon Research Conference: Human Single Nucleotide Polymorphisms & Disease
CONFERENCE 2014-08-03 00:00:00-2014-08-08 00:00:00 Stonehill College, Easton, Massachusetts 03 August 2014 to 08 August 2014 The conference will feature a wide range of topics, such as functional studies of human mutations, discriminating disease-causing and harmless mutations, characterizing common patte
TGF-β Gives TLC to Newborn Neurons
RESEARCH NEWS 2014-05-30 Research News Transforming growth factor-β (TGF-β), a cytokine that regulates cell growth and differentiation during development, appears to nurture adult neurogenesis. When scientists led by Tony Wyss-Coray, Stanford School of Medicine, California, dampe
PAPER He Y, Zhang H, Yung A, Villeda SA, Jaeger PA, Olayiwola O, Fainberg N, Wyss-Coray T
ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis.
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Age-dependent and differential effects of Smad7ΔEx1 on neural progenitor cell proliferation and on neurogenesis.
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Transcriptional basis for the inhibition of neural stem cell proliferation and migration by the TGFβ-family member GDF11.
PLoS One. 2013;8(11):e78478. Epub 2013 Nov 7 PubMed: 24244313Current Filters
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