Research Models

Prnp-APP

Synonyms: APP(Prnp), line A-2

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Species: Mouse
Genes: APP
Modification: APP: Transgenic
Disease Relevance: Alzheimer's Disease
Strain Name: B6.Cg-Tg(Prnp-APP)A-2Dbo/J
Genetic Background: C57BL/6
Availability: Jackson Labs: Stock# 006006; Cryopreserved

These mice express human APP driven by the mouse prion protein promoter. Hemizygous mice are viable and fertile, but phenotypic information is not available.

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References

External Citations

  1. Jackson Labs: Stock# 006006

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