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Fifth International Conference on Alzheimer's Disease and Related Disorders

24-29 July, 1996 Osaka, Japan

More than 1500 people have registered to attend this meeting, making it the largest ever convened in the field of Alzheimer's disease research. The Alzheimer Research Forum marks the public launch of its pilot World Wide Web site by featuring the following 12 presentations from the meeting. The recorded presentations will be edited into virtual slide talks and will be available on the site from around August 1. The presenters have agreed to respond to questions from the Web audience for an eight-week period after the conference.

The audio portions of the following presentations are in Real Audio format. To listen to Real Audio you will need to download and install the free Real Player.

• Synthesis and metabolism of presenilin 1 with mutations linked to familial Alzheimer's Disease in transgenic mice.
  David Borchelt (Sangram Sisodia presenting), Johns Hopkins Medical Institutions.
  (#95 (poster), 24 July, 16:00-18:00.)

• Evolution of Alzheimer's disease related intraneuronal changes.
  Heiko Braak, J.W. Goethe University.
  (#144 (plenary), 25 July 8:30-9:30.)

• The presenilin 1 and 2 mutations linked to familial Alzheimer's disease increase the extracellular concentration of amyloid beta protein ending at AB42(43).
  Steven Younkin, Mayo Clinic Jacksonville.
  (#149 (symposium), 25 July, 11:20-11:40.)

• Complete genomic screen in late-onset familial Alzheimer's disease.
  Margaret Pericak-Vance, Duke University Medical Center.
  (#233 (poster), 25 July, 16:00-18:00.)

• Involvement of tau protein kinase in Alzheimer's disease pathogenesis.
  Kazutomo Imahori, Mitsubishi Kasei Institute of Life Sciences.
  (#300 (symposium), 26 July, 11:20-11:40.)

• Estrogen, ApoE and the risk of Alzheimer's disease.
  Cornelia Van Duijn, Erasmus University Medical School. (#315 (oral), 26 July, 12:00-12:15.)

• Anti-inflammatory drug use and risk of incident Alzheimer's disease in a defined community population.
  Laurel A. Beckett, Rush University.
  (#318 (oral), 26 July, 12:45-13:00.)

• Cholinergic function and apoE polymorphism in Alzheimer's disease.
  Hilkka Soininen, University of Kuopio.
  (#540 (poster), 27 July, 9:30-11:30.)

• Two homologous genes associated with early onset familial Alzheimer's disease.
  Peter St. George-Hyslop, University of Toronto.
  (#610 (symposium), 28 July, 12:00-12:20.)

• Senile dementia with abundant neurofibrillary tangles without accompanying senile plaques. A new disease entity separable from SDAT?
  Kenji Ikeda, Tokyo Institute of Psychiatry.
  (#605 (symposium), 28 July, 11:20-11:40.)

• Proteolytic Processing of Wild-Type and Mutant Forms of Presenilin 2.
  Tae-Wan Kim, Massachusetts General Hospital and Harvard Medical School.
  (#624 (oral), 28 July, 12:30-12:45.)

• Monokines Reduce Accumulatoin of Beta-Peptide in Cultured Vascular Smooth Muscle Cells by Enhancing the Nonamyloidogenic Processing of Beta-APP.
  Janusz Frackowiak, New York State Institute for Basic Research in Developmental Disabilities.
  (#797 (oral), 29 July, 11:15-11:30.)