Shepherd C, McCann H, Halliday GM.
Variations in the neuropathology of familial Alzheimer's disease.
Acta Neuropathol. 2009 Jul;118(1):37-52.
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This is a very good summary of the neuropathologic features associated with cases of autosomal-dominant Alzheimer disease. Findings on the relationship of specific genetic mutations to neuropathologic features of AD provide some insight into the possible pathogenic mechanisms involved in common sporadic AD.