Vito P, Wolozin B, Ganjei JK, Iwasaki K, Lacanà E, D'Adamio L.
Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3.
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A key new lead. Specificity may be dependent on the PC12 line
This paper is most significant because they are dealing with a mouse homologue of a gene relevant to AD. More importantly, this work will lead to some important insights on cell death.