Sahara N, Vega IE, Ishizawa T, Lewis J, McGowan E, Hutton M, Dickson D, Yen SH. Phosphorylated p38MAPK specific antibodies cross-react with sarkosyl-insoluble hyperphosphorylated tau proteins. J Neurochem. 2004 Aug;90(4):829-38. PubMed.
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RIKEN Center for Brain Science
This paper together with their previous report (Sahara et al., 2002) implies a role for phosphorylation in tauopathy.
References:
Sahara N, Lewis J, Deture M, McGowan E, Dickson DW, Hutton M, Yen SH. Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility. J Neurochem. 2002 Dec;83(6):1498-508. PubMed.
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