. No disease in the brain of a 115-year-old woman. Neurobiol Aging. 2008 Aug;29(8):1127-32. PubMed.

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  1. These results fit well with our brain bank data: hippocampal tangles are always observed in aging, more or less. With amyloidosis, there is a development of the basic tauopathy, leading to Alzheimer disease.

    References:

    . Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease. Neurology. 2002 Aug 13;59(3):398-407. PubMed.

  2. In addition to this woman's brain, I hope that her eating habits, lifestyle, etc. can be investigated.

    View all comments by J. Lucy Boyd

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  1. Research Brief: Sharp and Amyloid-Free at 115