Giedraitis V, Hedlund M, Skoglund L, Blom E, Ingvast S, Brundin R, Lannfelt L, Glaser A.
New Alzheimer's disease locus on chromosome 8.
J Med Genet. 2006 Dec;43(12):931-5.
Please login to recommend the paper.
To make a comment you must login or register.
An interesting paper assessing a dozen Swedish families with AD in an attempt to identify a new locus. The authors present data that support (but do not prove) a new locus for AD on chr 8. This is based on a segregating haplotype across the centromere of chr 8 in two distinct families. As the authors note, more affected members or families and the identification of a single ancestral haplotype would strengthen this argument.