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Clarke EE, Churcher I, Ellis S, Wrigley JD, Lewis HD, Harrison T, Shearman MS, Beher D. Intra- or intercomplex binding to the gamma-secretase enzyme. A model to differentiate inhibitor classes. J Biol Chem. 2006 Oct 20;281(42):31279-89. PubMed. Recommends Please login to recommend the paper. Comments Boris Schmidt Darmstadt Technical University Posted: 02 Feb 2007 Finally, a very sound analysis provides a model to explain the strange pharmacology of gamma-secretase modulators and inhibitors. It can even incorporate the previous report on partial active site knock-outs. View all comments by Boris Schmidt Make a Comment To make a comment you must login or register.
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Darmstadt Technical University
Finally, a very sound analysis provides a model to explain the strange pharmacology of gamma-secretase modulators and inhibitors.
It can even incorporate the previous report on partial active site knock-outs.
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