. High prevalence of pathogenic mutations in patients with early-onset dementia detected by sequence analyses of four different genes. Am J Hum Genet. 2000 Jan;66(1):110-7. PubMed.

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Mutations

  1. PSEN1 F105L
  2. PSEN2 T122P
  3. PSEN1 A79V
  4. PSEN1 M139V