. Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathology. Nat Med. 2008 Oct;14(10):1106-11. Epub 2008 Sep 28 PubMed.


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  1. This seems to be a very interesting and consistent hypothesis opening exciting avenues for drug development. Potentially a breakthrough. Has it been possible to reconcile the data with the reference below?

    View all comments by Karl Naegler