. Familial patterns of risk in very late-onset Alzheimer disease. Arch Gen Psychiatry. 2003 Feb;60(2):190-7. PubMed.

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  1. I would like to underscore a
    point that is made at the end of the paper:

    The results of our study suggest that genetic risk factors play a much
    smaller role in AD with onset at or after age 85. If so, then this very
    late onset group of patients may be an ideal target population in which
    to further investigate environmentally mediated risk factors
    hypothesized to play a role in AD (e.g. many of the cardiovascular risk
     factors).

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