Zhang C, Browne A, Kim DY, Tanzi RE.
Familial Alzheimer's Disease Mutations in Presenilin 1 Do Not Alter Levels of the Secreted Amyloid-beta Protein Precursor Generated by beta-Secretase Cleavage.
Curr Alzheimer Res. 2009 Dec 1;
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This new analysis of the ways in which mutations known to cause familial AD influence the processing of amyloid beta will help understand the role of amyloid beta in causing this disease.