Kester MI, Boelaarts L, Bouwman FH, Vogels RL, Groot ER, van Elk EJ, Blankenstein MA, van der Flier WM, Scheltens P. Diagnostic impact of CSF biomarkers in a local hospital memory clinic. Dement Geriatr Cogn Disord. 2010;29(6):491-7. Epub 2010 Jun 3 PubMed.
AlzBiomarker Database
Meta-Analysis
Curated Study Data
| Biomarker (Source) |
Cohort (N) |
Measurement Mean ± SD |
Method; Assay Name; Manufacturer |
Diagnostic Criteria |
|---|---|---|---|---|
| Aβ42 (CSF) |
AD (47) |
492 ± 190 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| Aβ42 (CSF) |
DLB (11) |
516 ± 188 pg/mL § |
ELISA; Innotest; Innogenetics |
McKeith et al., 2005 |
| tau-p181 (CSF) |
AD (47) |
84 ± 50 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-p181 (CSF) |
DLB (11) |
44 ± 22 pg/mL § |
ELISA; Innotest; Innogenetics |
McKeith et al., 2005 |
| tau-total (CSF) |
AD (47) |
609 ± 342 pg/mL |
ELISA; Innotest; Innogenetics |
McKhann et al., 1984 |
| tau-total (CSF) |
DLB (11) |
352 ± 204 pg/mL § |
ELISA; Innotest; Innogenetics |
McKeith et al., 2005 |
§ Data supplied to Alzforum by author
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