D'Souza I, Schellenberg GD.
Determinants of 4-repeat tau expression. Coordination between enhancing and inhibitory splicing sequences for exon 10 inclusion.
J Biol Chem. 2000 Jun 9;275(23):17700-9.
PubMed.
The importance of the control of tau splicing is clearly critical to the understanding of tau biology in tangle diseases. This is a complex and tightly controlled process as this reference illustrates.
This represents a novel look at Tau regulation and sets the stage for regulating the number of repeats in tau (which affects its tendency to aggregate)
Comments
Institute of Neurology, UCL
The importance of the control of tau splicing is clearly critical to the understanding of tau biology in tangle diseases. This is a complex and tightly controlled process as this reference illustrates.
Boston University School of Medicine
This represents a novel look at Tau regulation and sets the stage for regulating the number of repeats in tau (which affects its tendency to aggregate)
Make a Comment
To make a comment you must login or register.