. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Hum Mol Genet. 2006 Sep 1;15(17):2560-8. PubMed.

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  1. From the AlzGene team:
    Note that only approximately 25-30 percent of the markers that were tested in the chromosome-wide association (CWA) analyses (Grupe et al., 2006 and Li et al., 2006) were also tested in the genome-wide association (GWA) study (Grupe et al., 2007). In particular, markers from the two "featured genes" identified in the CWA (in DAPK and LOC439999) were not included in the GWA. We thank Dr. Grupe for supplying this additional information.

    References:

    . A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. Am J Hum Genet. 2006 Jan;78(1):78-88. PubMed.

    . DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Hum Mol Genet. 2006 Sep 1;15(17):2560-8. PubMed.

    . Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. Hum Mol Genet. 2007 Apr 15;16(8):865-73. PubMed.