. Combined plasma biomarkers for diagnosing mild cognition impairment and Alzheimer's disease. ACS Chem Neurosci. 2013 Dec 18;4(12):1530-6. Epub 2013 Oct 23 PubMed.

AlzBiomarker Database

Meta-Analysis

Curated Study Data

Biomarker
(Source)
Cohort
(N)
Measurement
Mean ± SD
Method;
Assay Name;
Manufacturer
Diagnostic
Criteria
Aβ40
(Plasma)
AD
(30)
48.91 ± 29.7
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
McKhann et al., 2011
Aβ40
(Plasma)
AD
(31)
38.27 ± 9.15
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
McKhann et al., 2011
Aβ40
(Plasma)
CTRL-
CNC
(107)
71.44 ± 30.75
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
Aβ42
(Plasma)
AD
(30)
28.15 ± 25.64
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
McKhann et al., 2011
Aβ42
(Plasma)
AD
(31)
18.61 ± 1.55
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
McKhann et al., 2011
Aβ42
(Plasma)
CTRL-
CNC
(107)
15.29 ± 1.6
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
tau-total
(Plasma)
AD
(30)
73.01 ± 139.38
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
McKhann et al., 2011
tau-total
(Plasma)
AD
(31)
53.57 ± 22.87
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house
McKhann et al., 2011
tau-total
(Plasma)
CTRL-
CNC
(107)
16.16 ± 9.09
pg/mL §
Immunomagnetic Reduction;
Other/Not Specified;
In-house

§ Data supplied to Alzforum by author

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