. The capillary dysfunction hypothesis of Alzheimer's disease. Neurobiol Aging. 2013 Apr;34(4):1018-31. PubMed.

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  1. A fascinating paper describing how capillary dysfunction would be expected to initially lead to increased cerebral blood flow, followed by a transition to decreased blood flow as Alzheimer's disease progresses. The paper includes extensive and fascinating discussion of how many diverse observations fit into the authors' model.