. Alzheimer's second patient: Johann F. and his family. Ann Neurol. 2002 Oct;52(4):520-3. PubMed.


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  1. The second Alzheimer patient may well be a FAD case. It represents a "plaque only" case and I wonder if it's like the "cotton wool" plaques seen in some PS1 mutation. I hope someone can sequence the gene to find out.