Begley JG, Duan W, Chan S, Duff K, Mattson MP. Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice. J Neurochem. 1999 Mar;72(3):1030-9. PubMed.

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    • User Profile Image Hiroshi Mori
      Osaka City University Medical School
    • Posted:

    The paper shows that calcium ion is another central molecule besides superoxide for amyloid hypothesis.

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Research Models

  1. PS1(M146L)
  2. PS1(M146V)