Muresan V, Muresan Z.
Is abnormal axonal transport a cause, a contributing factor or a consequence of the neuronal pathology in Alzheimer's disease?.
Future Neurol. 2009 Nov 1;4(6):761-773.
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The authors state that “perturbation of the transport of a limited set of proteins has been occasionally reported for other neurodegenerative diseases [than Alzheimer's].” In fact, we have shown that the anterograde transport of distinct cargos is impaired in our K369I tau transgenic K3 mice and in Alzheimer disease brain.
Ittner LM, Fath T, Ke YD, Bi M, van Eersel J, Li KM, Gunning P, Götz J.
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia.
Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15997-6002. Epub 2008 Oct 2
Ittner LM, Ke YD, Götz J.
Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease.
J Biol Chem. 2009 Jul 31;284(31):20909-16.