Citation and Abstract


Clemmer DE, Valentine SJ. Bioanalytical chemistry: Protein oligomers frozen in time. Nature Chemistry. 2009 July 1;1(4):257-258.

 
  ABSTRACT
The size and shape of amyloid-beta protein assemblies have been studied using electrospray-ionization ion-mobility mass spectrometry, and the protein tetramers and dodecamers have been identified as an important oligomerization state in the development of neurodegenerative disease.