Irizarry MC, McNamara M, Fedorchak K, Hsiao K, Hyman BT.
APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.J Neuropathol Exp Neurol.
PubMed Abstract, View on AlzSWAN
An amazing technology used to show, once and for all, that plaques are dynamic structures. A great paper which subverts the huge literature seeking to correlate plaque numbers with clinical features. Pathology does not wait around to be counted!!!"