Sanz JM, Chiozzi P, Ferrari D, Colaianna M, Idzko M, Falzoni S, Fellin R, Trabace L, Di Virgilio F.
Activation of microglia by amyloid {beta} requires P2X7 receptor expression.J Immunol.
2009 Apr 1;182(7):4378-85.
PubMed Abstract
Excellent work by Williams and DeVirgilio. But what is the stimulant to the P2X7 receptor that stirs the immune cells in glia to activate from quiescence in AD?