Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Welge V, Fiege O, Lewczuk P, Mollenhauer B, Esselmann H, Klafki HW, Wolf S, Trenkwalder C, Otto M, Kornhuber J, Wiltfang J, Bibl M. Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease. J Neural Transm. 2009 Feb;116(2):203-12. PubMed Abstract

	Comments on Paper and Primary News

	Comment by: Richard C. Mohs, ARF Advisor (Disclosure)
	Submitted 20 January 2009 \| Permalink	Posted 23 January 2009
	I recommend this paper This paper presents data on the utility of CSF measures of amyloid β fragments and tau for the differentiation of cases of Alzheimer's from other clinical conditions. The data again show a marked reduction in Aβ in CSF from AD patients, but also show that a combination of Aβ fragments plus tau measures better differentiate AD from other chronic CNS conditions. View all comments by Richard C. Mohs

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