Higuchi M, Iwata N, Matsuba Y, Sato K, Sasamoto K, Saido TC.
19F and 1H MRI detection of amyloid beta plaques in vivo.Nat Neurosci.
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Used APP Tg2576 tg mice to study detection of amyloid b plaques. Demonstrated for the first time that 19F- and 1H MRI using a fluorine-containing amyloidophilic probe, FSB, can specifically and definitively identify amyloid b plaques in living mice.