Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu. - AlzForum Alzheimer Research Paper of the Week


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Home: Papers of the Week

Annotation

	Inestrosa NC, Reyes AE, Chacón MA, Cerpa W, Villalón A, Montiel J, Merabachvili G, Aldunate R, Bozinovic F, Aboitiz F. Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu. Neurobiol Aging. 2005 Jul;26(7):1023-8. PubMed Abstract

	Comments on Paper and Primary News

	Comment by: Jorge Parodi
	Submitted 14 March 2005 \| Permalink	Posted 14 March 2005
	I recommend this paper This is anew model, offering a new idea about Alzheimer disease. Maybe we can use a natural pathology to understand the disease in humans. View all comments by Jorge Parodi

	Comment by: George M. Martin, ARF Advisor (Disclosure)
	Submitted 16 March 2005 \| Permalink	Posted 18 March 2005
	We need more reports of the neuropathology of aging members of exotic mammalian species. Here is an example that deserves some further investigation as a model of AD. These Chilean "degus" are more closely related to guinea pigs than to lab mice or rats (D Huchon and EJP Douzery, Molecular Phylogenetics and Evolution, 20:238, 2001). View all comments by George M. Martin

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