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Home: Papers of the Week
Annotation


Raoul C, Estévez AG, Nishimune H, Cleveland DW, deLapeyrière O, Henderson CE, Haase G, Pettmann B. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron. 2002 Sep 12;35(6):1067-83. PubMed Abstract

  
Comments on Paper and Primary News
  Comment by:  Eddie Koo, ARF Advisor
Submitted 12 October 2002  |  Permalink Posted 12 October 2002
  I recommend this paper

A potential explanation for selective vulnerability of motoneurons in ALS. Whether the motoneurons cultured from embryos can be extended to other neurons in the body is unclear. The curious sparing of oculomotor neurons remains a big mystery to me.

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A Cell-Specific Death Program Claims Motoneurons
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