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Home: Papers of the Week
Annotation


Iadecola C, Zhang F, Niwa K, Eckman C, Turner SK, Fischer E, Younkin S, Borchelt DR, Hsiao KK, Carlson GA. SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein. Nat Neurosci. 1999 Feb;2(2):157-61. PubMed Abstract

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  Comment by:  Hiroshi Mori, ARF Advisor
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This is the first paper to show the significant function of APP in endothelial cells on AD pathogenesis.

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