Farr GW, Ying Z, Fenton WA, Horwich AL. Hydrogen-deuterium exchange in vivo to measure turnover of an ALS-associated mutant SOD1 protein in spinal cord of mice. Protein Sci. 2011 Oct;20(10):1692-6. PubMed Abstract
PRIMARY NEWSALS: Mutant Enzyme Does Not Hang Around, But Does Find Mitochondria