CONFERENCE COVERAGE SERIES
Keystone Symposium: ApoE, Alzheimer's, and Lipoprotein Biology
Keystone Resort, Keystone, CO, U.S.A.
26 February – 02 March 2012
What would be better, after an afternoon riding the ups and downs of the piste, than tackling the ins and outs of ApoE biology? Some 200 researchers did both in Keystone, Colorado, 26 February-2 March for the symposium, “ApoE, Alzheimer’s and Lipoprotein Biology.”
New data and debate trumped the freshly fallen snow, and left the impression that scientists are finally putting together a coherent picture of ApoE’s myriad roles in normal biology and neurodegenerative disease. [Image courtesy of Chen et al., 2010, National Academy of Sciences, U.S.A.]
Keystone: Symposium Emphasizes Key Aspects of ApoE Biology
Why has it been such a challenge to pinpoint the exact role in pathology of apolipoprotein E, which surpasses all other genetic risk factors for late onset Alzheimer’s disease?...
Keystone: Probing the Function of Lipoprotein and Related Receptors
Scientists are discovering just how intimately involved lipoprotein receptors are in the care and maintenance of neurons and their synapses...
Keystone: ApoE Receptors and Ligands in Memory and AD
Of the many facets of ApoE’s biology, the most complex one may be its activation of cell surface receptors...
Keystone: Does ApoE Fragmentation Drive Pathology?
Fragmentation can bog down your hard drive, and some scientists think it also wreaks havoc on processing in the brain...
Keystone: Therapies Around ApoE—Has Their Time Come?
Even though ApoE stands head and shoulders above other genetic risk factors for late-onset AD, few therapeutic strategies aimed at ApoE have made it to clinical trials...