Jobs

Postdoctoral Research Position in Biochemistry

Employer

Karolinska Institutet, Alzheimer Neurobiology Center

Location

Stockholm, Sweden

Contact

Applications and enquires should be addressed to Dr. Taher Darreh-Shori at taher.darreh-shori@ki.se, and contain the following documents:

  • Short cover letter describing interest in the position.
  • A complete curriculum vitae, including degrees and academic distinctions, date of the thesis defense, title of the thesis.
  • A complete list of publications.
  • A summary of current work (no more than one page).
  • Signed letters of recommendation and contact information from three researchers willing to serve as reference persons.

Description

We are looking for an enthusiastic and highly motivated scientist who is interested in working in a multi-disciplinary team at the forefront of translational Alzheimer's disease (AD) research. Our group aims to develop new diagnostic and prognostic biomarkers as well as novel treatment strategies that will delay or prevent the progression of the disease.

The focus of the research studies will be characterization and pharmacological analyses of certain target enzymes using cerebrospinal fluid (CSF), plasma, and postmortem brain tissues of patients with dementia such as AD and Lewy body dementia (LBD), with emphasis on cholinergic regulatory processes concerning neuroinflammation and functional status of cholinoceptive cells in the brain.

The aim is to improve our understanding of the underlying molecular pathophysiology in AD and LBD, which is critical in developing new diagnostic, prognostic, and therapeutic biomarkers for clinical use.

The environment provides excellent postdoctoral training in an international working environment, with national and international collaborations, and possibilities to publish in high-impact journals.

Requirements

Candidates must hold a non-Swedish Ph.D. or a foreign qualification deemed equivalent to a doctoral degree within the area of biomedical research with documented experience in neurochemistry, radio-ligand binding, and autoradiography assays and/or cell culture and immunochemistry studies, and have a strong interest in neurodegenerative diseases. Previous experience in protein signaling, and confocal microscopy is highly desirable.

The successful candidate will also be expected to have an established record of high-quality scientific research and publications, the ability to work both independently and as a member of a collaborative, scientific team, excellent verbal and written English skills, and the ability to write and apply for grants. The candidate should have completed his/her Ph.D. degree within three years before the last date for application. Candidates who have completed their degree earlier than this should receive equal priority if special grounds exist.

Postdoctoral scholarship will be awarded and the position is available immediately. The duration of the fellowship is up to 24 months. Educational scholarships are restricted for postdoctoral studies and may be awarded for up to two years in the five years following the public defense (or equivalent) of a doctoral thesis.

The scholarship amount is approved for six months at a time, is paid monthly and is exempted from Swedish income tax. Scholarships may not be given to anyone who in the two years before the proposed award of the scholarship has received a salary or remuneration from Karolinska Institutet.