Jobs

Associate Researcher Position

Employer

UCI MIND, Institute for Memory Impairments and Neurological Disorders

Location

Irvine, California, U.S.A.

Contact

Please submit a letter of interest, curriculum vitae that includes a record of research experience, and the names of three references before 8/31/2013 to: Dr. Frank LaFerla/ Andrea Wasserman Institute for Memory Impairments and Neurological Disorders UC Irvine, 2642 BS III, Zot Code: 4545 Irvine, CA 92697-4545. Email at laferla@uci.edu or awasserm@uci.edu

The University of California, Irvine is an equal-opportunity employer committed to excellence through diversity. Reference: OEOD # 6431.

Description

The University of California, Irvine’s Institute for Memory Impairments and Neurological Disorders has an opportunity for an associate reseracher. The scope of the research involves characterizing molecular pathways related to amyloid degradation, including expertise in well-described enzymes that are responsible for degrading Aß, such as insulin-degrading enzyme and neprilysin. The current project involves a multidisciplinary approach using animal and cellular models to elucidate the underlying molecular mechanisms by which Aß-degrading pathways are impacted using gene knockout and transgenic approaches, and to test mechanisms by which physical activity prevents cognitive decline. The successful candidate will be immediately responsible for designing and writing experimental protocols, conducting statistical analyses, and preparing manuscripts.

Requirements

Ph.D. in neuroscience with a focus on developing novel genetically modified animal models including conditional knockouts with additional expertise in behavioral testing of rodents, brain anatomy, and microdissection, and molecular work with RNA and protein, as well as in-depth knowledge and multiple years experience with microarray data analysis. Applicant must have a strong publication record in top-ranked journals, advanced writing skills, and many years experience with grant writing, including R01 grants. Job requires strong organizational skills as well as mentoring skills for undergraduate research students.

Essential skills include extensive hands-on experience in all aspects of animal-related research, with an emphasis on behavioral neuroscience techniques and quantitative assessment of cognitive endpoints. 

The position will be appointed at the level that is commensurate with the education and experience of the individual candidate.