Posted 16 Apr 2014
University of California, Irvine, Institute for Memory Impairments and Neurological Disorders
Irvine, California, U.S.A.
Please submit a letter of interest, curriculum vitae including a record of research experience, and the names of three references before April 20, 2014 to:
Dr. Frank LaFerla/Andrea Wasserman
Institute for Memory Impairments and Neurological Disorders
2642 Biological Sciences III
Irvine, CA 92697-4550
The associate researcher will lead projects that focus on investigating how proteins identified by Genome Wide Association studies (GWAS) in Alzheimer's disease contribute to AD risk as well as other neurological disorders. Projects should focus on aspects of synaptic function/plasticity, lipid metabolism, proteomic/metabolomics discovery, and endocytic dysfunction. The researcher will be responsible for experimental design, data analyses, and manuscript preparation, and will be expected to apply for both independent and collaborative funding to support his or her research focus.
A Ph.D. is required in biochemistry or molecular biology, with expertise in neurobiology, neuropathology and neurodegenerative diseases preferred. At least 10 years experience working with mouse models of Alzheimer disease and animal behavior is required.
We seek a candidate with stem cell-based research experience, in both mouse and human, with applications in novel in vitro culture systems i.e. microfluidics platforms. Experience in animal models of Alzheimer's disease with extensive knowledge of animal surgeries and behavior is highly desired, and experience studying both amyloid and tau neuropathology is a plus. The ideal candidate should have a strong background in biochemistry, molecular biology, and lipid chemistry.
This position will be appointed at the level that is commensurate with the education and experience of the individual candidate.