|
|
|
|
|
| First Name: | MOSUN | | Last Name: | AYAN-OSHODI | | Title: | Ms. | | Advanced Degrees: | MS | | Affiliation: | WALDEN UNIVERSITY | | Department: | GENERAL PSYCHOLOGY | | Street Address 1: | 5858 GUION LAKES CT | | City: | INDIANAPOLIS | | State/Province: | IN | | Zip/Postal Code: | 46254 | Country/Territory: | U.S.A. | | Phone: | 317-277-2528 | | Email Address: |  |
Disclosure:
(view policy)
|
|
Aging Process, Alzheimer Disease, Parkinson Disease
|
Genetics, A-beta PP/A-beta, Epidemiology, Tau/Cytoskeleton, Neurotransmission, Neurobiology, Neuroimmunology, Chemistry/Pharmacology, Clinical trials, Neuropathology
|
Pharmaceutical research-primary career
PhD student. General Psychology research and evaluation program |
Current Trends of APOE in familial Alzheimer's disease |
Fogarty, M. (2001) Genetic testing for people without symptoms of Alzheimer’s. Genetic Health
Genetic testing and Alzheimer's disease, (1998). Has the time come? Recommendations of the Stanford Program in Genomics, Ethics and Society, Nature Medicine 4, 757-759.
Henderson A.S. (1986). The epidemiology of Alzheimer's disease. British Medical Bulletin 42, 3-10.
Lindsay, J., Laurin, D., Verreault, R., Hebert, R., Helliwell, B., Hill, G. B., & McDowell, I. (2002). Risk factors for Alzheimer’s disease: a prospective analysis from the Canadian Study of Health and Aging. American Journal of Epidemiology. 156, 445-453.
Roberts, J.S., (2003). Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease. Alzheimer Disease and Associated. Disorders. 17, 86–93
|
Quantitative Evaluation of Apolipoprotein E (APOE) Risk Factor in Potential Familial Alzheimer’s disease.
Evidence to elivate general public awareness of genetic counseling |
Genetic factor component has been implicated in AD patients, the apolipoprotein (APOE) which is a low density lipoprotein receptor . The APOE genotyping included four difference alleles and e4 alleles have been implicated to predispose adult men and women with family history of AD to developing the disease.
The research question is to test the null and alternative hypothesis of changes in the plasma levels of APOE e4 allele in 30 adult men and women over the age of 55 years inclusive with family history of AD compared to 30 men and women without family history of AD (Lindsay, Laurin, Verreault, Hebert, Helliwell, Bill & McDowell, 2002; Creswell, 2003)
|
Need access to database to gather evidence |
Literature review for evidenced based information |
|
|
|
|
|
|
Home
