|
|
|
| First Name: | Patrick | | Last Name: | Kehoe | | Title: | Dr | | Advanced Degrees: | BSc J Hons PhD | | Affiliation: | University of Bristol | | Department: | Clinical Science at North Bristol | | Street Address 1: | John James Laboratories | | Street Address 2: | Frenchay Hospital | | City: | Bristol | | Zip/Postal Code: | BS16 1LE | Country/Territory: | United Kingdom | | Phone: | +441179186607 | | Fax: | +441179573955 | | Email Address: |  |
Disclosure:
(view policy)
|
Member reports no financial or other potential conflicts of interest. [Last Modified: 27 September 2006]
|
|
|
View all comments by Patrick Kehoe
|
Aging Process, Alzheimer Disease
|
Neurobiology, Genetics, Neuropathology, Epidemiology, Bioinformatics/Statistics, Proteomics, A-beta PP/A-beta, Molecular and Cell biology, Animal Models
|
Miners JS, Van Helmond Z, Chalmers KA, Wilcock GK, Love S, Kehoe PG (2006) Downregulation of neprilysin in Alzheimer's disease is associated with cerebral amyloid angiopathy and APOE e4. (JNEN In Press)
Kehoe, PG and Wilcock GK (2006) The Renin Angiotensin System in Alzheimer’s disease – Do updates highlight a clinical and biological dichotomy? Current Alzheimer’s Research 3; 2:171-173
Lehmann D, Cortina-Borja M, Warden DR, Smith AD, Sleegers K, Prince JA, van Duijn CM, Kehoe PG (2005) A meta-analysis confirms and clarifies the association of the ACE indel with Alzheimer’s disease. American Journal of Epidemiology 162; 4: 305-317.
Blomqvist M, Johanson A, Chalmers K, Andreasen N, Wilcock GK, Cairns NJ, Feuk L, Brookes AJ, Love S, Blennow K, Kehoe PG, Prince JA (2005) Sequence Variants of IDE Influence the Extent of -Amyloid Deposition in the Alzheimer’s Disease Brain. Neurobiology of Aging 26; 795-802.
Katzov H, Chalmers K, Johansson B, Cairns NJ, Gatz M, Wilcock GK, Love S, Pedersen NL, Brookes AJ, Blennow K, Kehoe PG, Prince JA (2004) Genetic Variants of ABCA1 modify Alzheimer’s Disease risk and quantitative traits related to it -amyloid metabolism. Human Mutation 23,4: 358-367.
Kehoe PG, Katzov H, Andreason N, Gatz M, Wilcock GK, Cairns NJ, Palmgren J, de Faire U, Brookes AJ, Pedersen NL, Blennow K, Prince JA (2004) Genetic Variants of ACE Contribute to Age at Onset in Alzheimer's Disease. Journal of Medical Genetics 114, 5: 478-483.
Kehoe PG, Katzov H, Feuk L, Bennet AM, Johansson B, Wiman B, de Faire U, Cairns NJ, Wilcock GK, Brookes AJ, Blennow K, Prince JA (2003) Haplotypes extending across ACE are associated with Alzheimer's disease. Human Molecular Genetics; 12, 8:859-867
Kehoe PG, Russ C, McIlory S, Williams H, Holmans P, Holmes C, Liolitsa D, Vahidassr D, Powell J, McGleenon B, Liddell M, Plomin R, Dynan K, Williams N, Neal J, Cairns NJ, Wilcock G, Passmore P, Lovestone S, Williams J, Owen MJ. (1999). Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer’s disease. Nature Genetics; 21: p71-72
Kehoe P, Wavrant-De Vrieze F, Crook R, Wu WS, Holmans P, Fenton I, Spurlock G, Norton N, Williams H, Williams N, Lovestone S, Perez-Tur J, Hutton M, Chartier-Harlin MC, Shears S, Roehl K, Booth J, Van Voorst W, Ramic D, Williams J, Goate A, Hardy J, Owen MJ. (1999). A Full Genome Scan for Late Onset Alzheimer’s Disease. Human Molecular Genetics; 8: p237-245
|
|
|
Home
