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| First Name: | Josep | | Last Name: | Saura | | Title: | PhD | | Affiliation: | University of Barcelona | | Department: | Biochemistry Unit, School of Medicine | | Street Address 1: | Casanova 143 | | City: | Barcelona | | State/Province: | Spain | | Zip/Postal Code: | E-08036 | Country/Territory: | Spain | | Email Address: |  |
Disclosure:
(view policy)
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Member reports no financial or other potential conflicts of interest. [Last Modified: 3 March 2008]
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Neuromuscular Disorders (ALS, etc.), Alzheimer Disease, Parkinson Disease
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Animal Models, A-beta PP/A-beta, Neuroimmunology, Molecular and Cell biology, Neurobiology
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3. SAURA J, KETTLER R, DA PRADA M, RICHARDS JG (1992) Quantitative enzyme radioautography with [3H]Ro41-1049 and [3H]Ro19-6327 in vitro: Localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs and human brain. J.Neurosci.12; 1977-1999.
5. SAURA J*, LUQUE JM*, CESURA AM, DA PRADA M, CHAN-PALAY V, HUBER G, LÖFFLER J, RICHARDS JG (1994) Increased MAO-B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. Neuroscience 62; 15-30.
10. SAURA J, ANDRÉS N, ANDRADE C, OJUEL J, ERIKSSON K, MAHY N. (1997) Biphasic and region-specific MAO-B response to aging in control human brain. Neurobiol.Aging 18; 497-507
13. WALTON M, SAURA J, YOUNG D, MACGIBBON G, HANSEN W, LAWLOR P, SIRIMANNE E, GLUCKMAN P, DRAGUNOW M. (1998) CCAAT-enhancer binding protein is expressed in activated microglial cells after brain injury. Mol. Brain Res. 61; 11-22.
16. BALES KR, VERINA T, CUMMINS DJ, DU Y, DODEL RC, SAURA J, FISHMAN CE, DELONG CA, PICCARDO P, PETEGNIEF V, GHETTI B, PAUL SM (1999) Apolipoprotein E is essential for amyloid deposition in the APPV717F transgenic mouse model of Alzheimer's disease. Proc. Natl. Acad. Sci. USA 96; 15233-15238.
25. SAURA J, PARÉS M, BOVÉ J, PEZZI S, ALBERCH J, MARIN C , TOLOSA E, MARTÍ MJ (2003) Intranigral infusion of interleukin-1 activates astrocytes and protects from subsequent 6-hydroxydopamine neurotoxicity. J.Neurochem 85; 651-661
26. SAURA J*, PETEGNIEF V*, WU, X, LIANG Y, PAUL SM (2003) Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro: opposite effects of lipopolysaccharide. J.Neurochem 85; 1455-1467
27. SAURA J, TUSELL, JM, SERRATOSA J (2003) High-yield isolation of murine microglia by mild trypsinization. GLIA 44; 183-189
29. SAURA J, ANGULO E, EJARQUE A, CASADÓ V, TUSELL JM, MORATALLA R, CHEN, JF, SCHWARTZSCHILD MA, LLUIS C, FRANCO R, SERRATOSA J. (2005) A2A receptor stimulation potentiates NO release by activated microglia.
J Neurochem 95; 919-929.
32. EJARQUE-ORTIZ A, MEDINA MG, TUSELL JM, PÈREZ-GONZÁLEZ AP, SERRATOSA J, SAURA J (2007) Upregulation of CCAAT/enhancer binding protein beta in activated astrocytes and microglia. GLIA 55; 178-88.
36. SAURA J (2007) Microglial cells in astroglial cultures: a cautionary note. J Neuroinflammation 4; 26.
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Glial activation plays a pathogenic role in neurodegenrative diseases |
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