The Antibodies database was archived in December 2022 and is no longer being updated. The Antibodies database is being supplanted by the AlzAntibodies database, which aims to provide detailed descriptions of selected antibodies.

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Antibodies

52 Results

Name Source Clonality &
Isotype
Host &
Formulation
Method Reactivity Immunogen/
Epitope
Specificity Availability
Sirtuins From manufacturers (52)
Abcam polyclonal
IgG
Rabbit
(liquid, whole antiserum, PBS, BSA, azide)
- Human Immunogen = two synthetic peptides, conjugated to KLH, derived from within residues 1 - 50 and 450-610 of human SIRT1 SIRT1 -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
- Mouse Immunogen = synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal aa 722-737 of mouse SIRT1 SIR2 -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified)
- Human Immunogen = peptide mapping to the C-terminal domain of human SIRT1 SIRT1 -
ABGENT polyclonal
Ig
Rabbit
(liquid, PBS, azide, Protein G purified)
- Human Immunogen = synthetic peptide (10-30 aa in length) at the C-term of last 100 aa of human Sirt1, KLH coupled SIRT1 -
Biomol Enzo Life Sciences polyclonal
Rabbit
(liquid, immuno-depleted antiserum, PBS)
- Human Immunogen = recombinant human SIRT1 SIRT1 (recombinant and native). No cross-reactivity with recombinant human SIRT2, SIRT3 or SIRT5. -
AMS Biotechnology polyclonal
Ig
Rabbit
(liquid, PBS, azide, Protein G purified)
- Human Immunogen = synthetic peptide (10-30 aa in length) at the C-term of last 100 aa of human Sirt1, KLH coupled SIRT1 -
Autogen Bioclear polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide)
- Human, Mouse, Rat Immunogen = amino acids 448-747 of human SIRT1 SIRT1 -
Delta Biolabs polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified)
- Human Immunogen = peptide mapping to the C-terminal domain of human SIRT1 SIRT1 -
GeneTex polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
- Mouse Immunogen = synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal aa 722-737 of mouse SIRT1 SIR2 -
GeneTex polyclonal
IgG
Rabbit
(liquid, whole antiserum, PBS, BSA, azide)
- Human Immunogen = two synthetic peptides, conjugated to KLH, derived from within residues 1 - 50 and 450-610 of human SIRT1 SIRT1 -
GeneTex polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified)
- Human Immunogen = peptide mapping to the C-terminal domain of human SIRT1 SIRT1 -
IBL polyclonal
IgG
Rabbit
(purified, BSA, PBS, azide, lyophilized)
- Human Immunogen = Synthetic peptides for part of C Terminal of human Sir2/SIRT1(LEDEPDV PERAGG) Sir2/SIRT1 -
I B L-America polyclonal
IgG
Rabbit
(affinity purified, BSA, PBS, azide, lyophilized)
- Human Immunogen = Synthetic peptides for part of C Terminal of human Sir2/SIRT1(LEDEPDV PERAGG) Sir2/SIRT1 -
Insight Biotechnology polyclonal
IgG
Rabbit
(PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = aa 448-747 of SIRT1 of human origin SIRT1 -
Insight Biotechnology polyclonal
IgG
Goat
(PBS, azide, gelatin, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping within an internal region of SIRT1 of human origin SIRT1 -
Insight Biotechnology polyclonal
IgG
Goat
(PBS, azide, gelatin, affinity purified)
- Human immunogen = peptide mapping near the C-terminus of SIRT1 of human origin SIRT1 -
Epitomics monoclonal
IgG
Rabbit
(liquid, tris-glycine saline, glycerol, azide, BSA)
- Human immunogen = synthetic peptide corresp. to residues in C-terminus of human Sir2/SIRT1 SIRT1; no cross-reaction with other sirtuin family members -
Epitomics monoclonal
IgG
Rabbit
(liquid, tris-glycine saline, glycerol, BSA, azide)
- Human immunogen = synthetic peptide corresp. to residues near N-terminus and before Ala-rich domain of human Sir2 Sir2/SIRT1 -
Insight Biotechnology monoclonal
IgG
Rabbit
(liquid, tris-glycine saline, glycerol, azide, BSA)
- Human immunogen = synthetic peptide corresp. to residues in C-terminus of human Sir2/SIRT1 SIRT1; no cross-reaction with other sirtuin family members -
Insight Biotechnology monoclonal
IgG
Rabbit
(liquid, tris-glycine saline, glycerol, BSA, azide)
- Human immunogen = synthetic peptide corresp. to residues near N-terminus and before Ala-rich domain of human Sir2 Sir2/SIRT1 -
Insight Biotechnology polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified)
- Human immunogen = peptide mapping to the C-terminal domain of human SIRT1 SIRT1 -
Sigma Aldrich monoclonal
IgG1
Mouse
(liquid, PBS, azide)
- Mouse immunogen = synthetic peptide corresp. to aa. 722-737 at the C-terminus of mouse Sir2 with C-terminal added lysine SIRT1 -
Interchim polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
- Mouse Immunogen = synthetic peptide: A T R Q E L T D V N Y P S D K S (with C-terminal added lysine), corresp. to C terminal aa 722-737 of mouse SIRT1 SIR2 -
Interchim polyclonal
Rabbit
- Human Immunogen = within aa 646-660 - -
Acris Antibodies polyclonal
IgG
Rabbit
(liquid, PBS, gelatin, azide, affinity purified)
- Human Immunogen = peptide mapping to the C-terminal domain of human SIRT1 SIRT1 -
MBL International polyclonal
IgG
Rabbit
(DEAE purified, phosphate buffer, glycerol)
- Human Immunogen = recombinantfull length SIRT detects endogenous levels of SIRT1 protein; does not cross-react with type I and II HDAC proteins. -
Orbigen polyclonal
Rabbit
(liquid, PBS, azide, protein-G purified)
- Human Immunogen = KLH conjugated synthetic peptide comprised of aa 646 - 660 [PPNRYIFHGAEVYSD] of human SIRT1 SIRT1 -
tebu-bio polyclonal
Rabbit
(liquid, immuno-depleted antiserum, PBS)
- Human Immunogen = recombinant human SIRT1 SIRT1 (recombinant and native). No cross-reactivity with recombinant human SIRT2, SIRT3 or SIRT5. -
tebu-bio polyclonal
IgG
Goat
(PBS, azide, gelatin, affinity purified)
- Human immunogen = peptide mapping near the C-terminus of SIRT1 of human origin SIRT1 -
tebu-bio polyclonal
IgG
Goat
(PBS, azide, gelatin, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping within an internal region of SIRT1 of human origin SIRT1 -
tebu-bio polyclonal
IgG
Rabbit
(PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = aa 448-747 of SIRT1 of human origin SIRT1 -
Biomol Enzo Life Sciences kit
Unknown Host
(complete assay system designed to measure the lysyldeacetylase activity of recombinant human SIRT1)
- - - SIRT1, recombinant -
tebu-bio kit
Unknown Host
(complete assay system designed to measure the lysyldeacetylase activity of recombinant human SIRT1)
- - - SIRT1, recombinant -
US Biological monoclonal
IgG1
Mouse
(liquid, PBS, protein G affinity purified)
- Human immunogen = synthetic peptide corresponding to aa 551–599 of human silent information regulator 2 homolog (Sirt1) protein, ovalbumin-conj. Sirt1 (120kDa) -
US Biological polyclonal
IgG
Rabbit
(liquid, serum)
- Human immunogen = a mixture of two peptides: 1. G A D R E A A S S P A G E P (aa 22-32) 2. M E N P D L K N V G S S T G E K (aa 595-610), KLH-conjugated; GenBank# NP_036370 Sirt1 -
US Biological monoclonal
IgG1
Mouse
(liquid, PBS, glycerol, azide, affinity purified)
- Human immunogen = synthetic peptide corresponding to aa551-599 of human Sirt1, ovalbumin-conjugated Sirt1 (120kDa and unidentified band at 100kDa) -
Austral Biologicals monoclonal
IgG1
Rabbit
(liquid, IgG fraction, Protein G purified)
- Human Immunogen = synthetic peptide corresp. to aa 551-599 of human Sirt1, ovalbumin conj. 120 kDa SIRT1 -
Abcam monoclonal
IgG
Rabbit
(liquid, tris-glycine, BSA, glycerol, azide)
- Human immunogen = synthetic peptide corresp. to residues in C-terminus of human Sir2/SIRT1 SIRT1; no cross reaction with sirtuin family members -
Abcam monoclonal
IgG
Rabbit
(liquid, tris-glycine saline, BSA, glycerol, azide)
- Human immunogen = synthetic peptide corresponding to residues near N-terminus and before Ala-rich domain of human Sir2. SIRT1; no cross-reaction with other sirtuin family members -
Abcam polyclonal
IgG
Rabbit
(liquid, PBS, BSA, azide, affinity purified)
- Mouse immunogen = synthetic peptide conjugated to KLH derived from within residues 700 to the C-terminus of mouse SIRT1 SIRT1 -
Santa Cruz polyclonal
IgG
Goat
(PBS, azide, gelatin, affinity purified)
- Human immunogen = peptide mapping near the C-terminus of SIRT1 of human origin SIRT1 -
Santa Cruz polyclonal
IgG
Goat
(PBS, azide, gelatin, affinity purified)
- Human, Mouse, Rat immunogen = peptide mapping within an internal region of SIRT1 of human origin SIRT1 -
Santa Cruz polyclonal
IgG
Rabbit
(PBS, azide, gelatin)
- Human, Mouse, Rat immunogen = aa 448-747 of SIRT1 of human origin SIRT1 -
None polyclonal
Rabbit
(liquid, affinity purified, PBS, azide, gelatin)
- Human immunogen = peptide mapping to the carboxy terminal domain of human SIRT1 recognizes human SIRT1 protein Discontinued
Novus Biologicals monoclonal
IgG1
Mouse
(liquid, purified IgG, no preservative)
- Human Immunogen = partial recomb. SIRT1 (456 aa. ~ 555 aa.) with GST tag SIRT1 -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, TBS, BSA, azide, affinity purified)
- Human Immunogen = peptide mapping to a region between residue 25 and 75 of human SIRT1 Sirt1, nuclear -
Novus Biologicals polyclonal
IgG
Rabbit
(liquid, TBS, BSA, azide, affinity purified)
- Human Immunogen = peptide mapping to a region between residue 700 and the C-terminus (residue 747) of human SIRT1 Sirt1, nuclear -
Novus Biologicals polyclonal
Mouse
(liquid, antisera, glycerol, no preservative)
- Human Immunogen = partial recomb. SIRT1 SIRT1 -
Chemicon and Upstate are Millipore monoclonal
IgG1
Mouse
(liquid, PBS, glycrol, azide, Protein G purified)
- Human Immunogen = peptide corresp. to aa 551-599 of human Sirt1 SIRT1(120kDa by WB). An additional unidentified band was detected (100 kDa). -
Chemicon and Upstate are Millipore monoclonal
IgG
Rabbit
(liquid, Tris-Glycine, saline, BSA, glycrol, azide)
- Human Immunogen = synthetic peptide corresponding to residues near C-terminus and before Ala-rich domain of human Sir2 recognizes SIRT1(~110 kDa by WB); does not cross-react with other sirtuin family members. -
Chemicon and Upstate are Millipore monoclonal
IgG,κ
Mouse
(liquid, purified, Tris-Glycine, saline, azide)
- Human, Mouse Immunogen = His-tagged recombinant protein corresponding to human SIRT1; mouse sequence is 100% identical to immunogen recognizes SIRT1 -
Chemicon and Upstate are Millipore polyclonal
IgG
Rabbit
(liquid, purified, Tris-Glycine, saline, azide, glycerol)
- Human, Mouse Immunogen = His-tagged fusion protein corresponding to amino acids 1-131 of mouse Sir2α recognizes SIRT1, ~110 kDa -