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NO Parkin—A Simple Modification Arrests Ligase

The clamp, the boot, whatever you call it, if you find one on your car you’ll appreciate how a seemingly small attachment can keep its wheels from turning. In today’s Sciencexpress, researchers report that covalently clamping parkin with nitric oxide...

NGF Gene Therapy Trial Begins

The green light has been given for Mark Tuszynski and his colleagues from the University of California, San Diego, the Salk Institute, and UC Davis to start a Phase I (safety) trial of nerve growth factor (NGF) gene therapy for early onset Alzheimer's...

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