Paper Alert: Malformed Mitochondria in the Latest TDP-43 Mouse
There is a new TDP-43 mouse in town...
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There is a new TDP-43 mouse in town...
A γ-secretase inhibitor that doesn’t block γ-secretase may seem like a bit of an oxymoron, but there are some compounds that appear to do just that...
A new study suggests that age-related protein aggregation might be widespread even in healthy organisms...
In clinical research, a first-time finding may rouse intrigue, but it’s generally independent confirmations of the data that give them potential to leave an indelible mark...
Honolulu: FDA Approval in Sight for 18F Amyloid Tracer Florbetapir? Honolulu: Tomm40 Reported to Track With Brain Atrophy, Cognition Honolulu: TrialMatch Launched as AD Is Becoming “Desktop” Disease Honolulu: The Missing Link? Tau Mediates Aβ Toxicity at
Top-line data announced this week from a Phase 2 clinical trial of the drug scyllo-inositol give cause to move to Phase 3...
Yet again, lithium has failed to live up to its promise in the treatment of amyotrophic lateral sclerosis...
Scientists have drafted a new set of diagnostic research criteria redefining AD as a condition that develops decades prior to obvious symptoms...
Researchers are sliding electrodes into the brains of people with Alzheimer disease, hoping to awaken memories and stave off disease-induced forgetfulness...
Beyond the lab mouse, AD researchers may have access to a growing repertoire of brainier, brawnier species for their in vivo studies...
ALS is tragic when it hits in late or middle age, but a rare juvenile form of the disease is all the more devastating...
Antibodies to synthetic Aβ oligomers, or “globulomers,” improve cognition in a mouse model of Alzheimer disease...
Paralysis is not always a bad thing—during sleep, it is essential to prevent us from acting out our dreams...
A comprehensive proposal of new diagnostic criteria marked a highlight at the International Conference on Alzheimer’s Disease...
Three workgroups of clinicians from the U.S. and Europe offered new guidelines for the diagnosis of AD...
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