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NGF Gene Therapy Trial Begins

The green light has been given for Mark Tuszynski and his colleagues from the University of California, San Diego, the Salk Institute, and UC Davis to start a Phase I (safety) trial of nerve growth factor (NGF) gene therapy for early onset Alzheimer's...

Aβ Primes an Inflammatory Pump

A paper in today's Science offers a candidate pathway for inflammatory processes in Alzheimer's disease; the pathway uses the CD40 receptor on microglia and is upregulated by Aβ...

Toward a Unified Prion Theory

A report in today's Nature shows that prion forms found in apparently anomalous prion diseases are likely to represent the common final path to neurodegeneration in all the spongiform encephalopathies...

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