Alpha-secretase does not necessarily pick up the slack when β-secretase cleavage of amyloid precursor protein wanes, a study in primates finds. It suggests APP can be processed in other ways.
Belying some earlier reports, a new study finds that grafted dopamine cells continue to innervate neural networks years after transplantation.
An amplification-based test picks up minute amounts of prion protein in the blood of asymptomatic carriers, but researchers wonder whether regulators will want to screen the population.
Patient-derived macrophages are the latest model of Gaucher’s disease, a lysosomal storage disorder. The cells may help researchers better understand disease phenotypes and test candidate therapies.
Does amyotrophic lateral sclerosis start at the interface between mitochondria and the endoplasmic reticulum?
While scientists remain on the fence over whether computer games benefit cognition, some are finding new uses for gaming data in clinical trial research.
Brain-training websites tout their games’ potential to boost cognition, but strong evidence and firm backing by the scientific community have yet to surface.